The name of this type of bacteria is given in honor of the English bacteriologist David Bruce, who in 1884-1889 discovered Brucella to the world. They differ in various shapes: they are spherical, oval and in the form of sticks. They are motionless, do not form spores, lack flagella, can exist both in the presence of oxygen and without it, live inside cells. Able to move into rough and wallless forms. Contain antigens - smooth lipopolysaccharide (LPS) of the outer membrane and internal proteins.
Brucellosis (Bang's disease, Maltese, Cypriot or Mediterranean fever) is an infectious disease caused by various types of Brucella. Gram-negative, i.e., not detected by Gram staining, but susceptible to aniline dyes. When decomposed, they form a bacterial toxic substance "endotoxin". Grows slowly on nutrient media: 1-3 weeks on hepatic agar with sugar and glycerol (optimal temperature for growth 37°C).
The source of infection are domestic animals (goats, sheep, cows, pigs, dogs, etc.). It is not transmitted from person to person (with the exception of intrauterine infection). Susceptibility to infection is high, immunity is short (up to a year), which is why re-infection is possible. Three species of Brucella (Br. abortus, Br. melitensis and Br. suis) may be potential agents of bioterrorism. The incubation period lasts from six days to two months. With the primary latent (hidden) form of omeprazole pills, it can take months before the onset of symptoms. Subacute and acute brucellosis.
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Symptoms of brucellosis can be quite varied, some persist for a long time. Body temperature rises rapidly and rises to 40 ° C and above, it is characterized by a wave-like course with consistently good health.
The onset of brucellosis in humans is acute or subacute. This period is characterized by: Approximately three out of four patients can indicate the day and hour of the appearance of the first signs of brucellosis, but this should be treated critically, since relatively good health is typical for the onset of the development of the pathology, even at high temperatures.
Sweating increases and persists, irritability, appetite and sleep disturbance, and fatigue gradually increase. Over time, pains appear in large joints and muscles (dull,long, distinctly associated with weather changes). The joints become swollen, painful when probing (due to the growth of bone tissue), mobility is limited, the skin over the joints does not change. Objectively, the patient is in a clear mind, in a relatively satisfactory condition, no external signs of the disease can be visually noted.
In the study of peripheral lymph nodes, small, weakly sensitive dense lymph nodes are found everywhere, but this happens infrequently. In half of the cases, the liver and spleen are moderately enlarged.